Transcription factor heterogeneity and epiblast pluripotency
نویسندگان
چکیده
منابع مشابه
Transcription factor heterogeneity and epiblast pluripotency.
Stem cells are defined by the simultaneous possession of the seemingly incongruent properties of self-renewal and multi-lineage differentiation potential. To maintain a stem cell population, these opposing forces must be balanced. Transcription factors that function to direct pluripotent cell identity are not all equally distributed throughout the pluripotent cell population. While Oct4 levels ...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society B: Biological Sciences
سال: 2011
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2011.0043